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Converting from other opioids to OPANA ER

* Ratio for conversion of oral opioid dose to approximate OPANA ER equivalent dose. Select opioid and multiply the dose by the conversion ratio to calculate the approximate oral oxymorphone equivalent.

† It is extremely important to monitor all patients closely when converting from methadone to other opioid agonists. The ratio between methadone and other opioid agonists may vary widely as a function of previous dose exposure. Methadone has a long half-life and tends to accumulate in the plasma.

The conversion ratios and approximate equivalent doses in this conversion table are only to be used for the conversion from current opioid therapy to OPANA ER.

To convert from other opioids to OPANA ER, please use our new dosage conversion calculator.

Converting from OPANA to OPANA ER1

Administer half the patient’s total daily oral OPANA dose as OPANA ER every 12 hours.

Select

Hydrocodone

Methadone

Morphine

Oxycodone

Oxymorphone


References

  1. OPANA ER Full Prescribing Information. Chadds Ford, Pa: Endo Pharmaceuticals; 2008.